近日,中国热科院海口站西番莲育种团队筛选出参与黄酮类化合物和萜类化合物合成途径的候选基因,解析了西番莲中三萜类的生物合成途径,为进一步挖掘西番莲关键基因的功能奠定了基础。 西番莲(Passiflora edulis Si...
阅读全文急性随性白血病(AML)是一种最常见且最具侵袭性的急性白血病,患者的5年存活率仅为24%;近日,一篇发表在国际杂志Molecular & Cellular Proteomics上题为“Synergistic Targeting of DNA-PK and KIT Signaling Path...
阅读全文《细胞研究》:科学家首次证实,阿司匹林能促进DNA双链断裂高保真修复 事实确实如此,阿司匹林处理导致Ac-H4K16水平升高,促进同源重组修复蛋白BRCA1在断裂处聚集。 德国弗莱堡大学医学中心Nelson O Gekara团队在著...
阅读全文众所周知,消化道中肿瘤细胞对铁离子的过量吸收在驱动结直肠癌发生上扮演着非常重要的角色,结直肠癌是美国第三大流行的疾病同时也是第三大癌症死亡的原因。近日,一篇发表在国际杂志Advanced Science上题为“Transf...
阅读全文中国医科大学研究者总结了免疫检查点B7-H3(CD276)研究和药物开发的新前沿 支持免疫系统杀死癌症细胞是一种很有前景的癌症治疗策略。免疫检查点(如PD-1、PD-L1、CTL4)调节免疫系统,对自我耐受、防止自身免疫和抵...
阅读全文自然界中,体色多态性广泛存在于昆虫、鱼类、两栖类、爬行类、鸟类和哺乳类等几乎所有动物类群,这些丰富色彩的形成机制备受关注。爬行动物的颜色或斑纹主要由发育自神经嵴细胞的3种色素细胞(黑色素细胞、黄色素细胞...
阅读全文红细胞是人体中数目最多的细胞,也是体内最活跃的自我更新体系,健康人每日需更新约二十亿个红细胞。红细胞发育过程的缺陷会导致许多贫血或再生不良的疾病发生,例如先天性纯红再障(DBA)等[1-3],因此理解红细胞发...
阅读全文在一项新的研究中,来自美国德克萨斯大学西南医学中心的研究人员指出称为滤泡(blebs)的细胞膜突起通常意味着健康细胞生命的结束,但对黑色素瘤细胞却相反,激活细胞中的这些突起,帮助它们生存和扩散。这些研究结果...
阅读全文Credit: Pixabay/CC0 Public Domain Many people are flocking to the Gulf Coast for spring break. However, toxic red tide algal blooms have put beachgoers and residents on alert. In the Gulf of Mexico,...
阅读全文Graphical Abstract. Credit: Cell Stem Cell (2023). DOI: 10.1016/j.stem.2023.02.010 In humanity's ongoing quest for the elixir of life, the science keeps pointing to stem cells. Research increasingly s...
阅读全文The Gray-chinned Minivet displays a secondary non-breeding season peak, which is possibly related to flocking behavior. Credit: Shih-Hung Wu, Ph.D. Candidate Montane forests, known as biodiversity hot...
阅读全文Forests and trees offer shade, food and water in regions suffering increasingly from drought and heat, such as Morocco, but are threatened at the same time. Credit: Alexander Buck The global scientifi...
阅读全文The extraterrestrial processes responsible for influencing the diversity of life forms are usually invisible to the human eye. The Milky Way is where large stars explode, leading to supernova remnants...
阅读全文Microscopic cross-section of the beetle's hindgut. The picture shows the dry stool in magenta colors surrounded by the intestine in gray. The malpighian tubule of the beetle is seen in purple. Credit:...
阅读全文Credit: CC0 Public Domain With ice declining, bowhead whales of the Pacific Arctic are staying longer in the waters up north. A change in migration patterns could affect the bowheads' health and safet...
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